Dose Titration Planner

Your label-based escalation ladder, mapped week by week.

Projected ladder — 4 weeks per step

  1. 2.5 mgyou are here

    Starter — tolerance, not effect

    started

  2. 5 mg

    ≈ Aug 9, 2026

  3. 7.5 mg

    ≈ Sep 6, 2026

  4. 10 mg

    ≈ Oct 4, 2026

  5. 12.5 mg

    ≈ Nov 1, 2026

  6. 15 mg

    Max maintenance

    ≈ Nov 29, 2026

These are the earliest label-eligible dates — each step is held at least 4 weeks. Your prescriber may hold you longer for side effects or results. Never step up early on your own.

How GLP-1 dose escalation works

Both semaglutide and tirzepatide start low on purpose. The opening dose (0.25 mg semaglutide, 2.5 mg tirzepatide) isn't meant to drive much weight loss — it's a tolerance step that lets your gut adjust and keeps nausea manageable. From there the label steps you up roughly every four weeks, provided you're tolerating the current dose.

The ladders

Semaglutide (Ozempic / Wegovy): 0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg. Tirzepatide (Mounjaro / Zepbound): 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg. The planner maps these onto a calendar from your start date so you can see, concretely, when each step could arrive and when you might reach the maintenance dose.

Why the four-week hold matters

These medications take about 4–6 weeks to reach steady state at each dose. Stepping up before then stacks a rising blood level on top of one that hasn't settled — which is how side effects spike. That's why the dates here are the earliest your prescriber could move you up, not a schedule to enforce yourself. Plenty of people hold longer, and that's fine.

Frequently asked

How long do you stay on each GLP-1 dose?
Usually at least 4 weeks per step, so the medication reaches steady state and side effects settle before increasing. Some people hold a dose longer if side effects linger or their results are on track.
Can I skip a titration step to lose weight faster?
No. Skipping steps sharply raises the risk of nausea, vomiting, and dehydration without improving long-term results. The ladder exists to keep escalation tolerable — only your prescriber should change it.
What are the standard tirzepatide and semaglutide dose steps?
Tirzepatide (Mounjaro/Zepbound): 2.5, 5, 7.5, 10, 12.5, and 15 mg. Semaglutide (Ozempic/Wegovy): 0.25, 0.5, 1.0, 1.7, and 2.4 mg. Each is typically held around four weeks.
Does everyone go all the way to the maximum dose?
No. Many people reach their goals and settle at a middle dose. The maintenance dose is whatever controls appetite and sustains progress with tolerable side effects — that is a decision for you and your prescriber, not a target to rush toward.

Medical disclaimer. Tiro is a tracking companion, not a medical device, and nothing on this site is medical advice. Always follow the titration schedule and dosing instructions from your prescriber. Never change your dose without talking to them first.